Goat Secondary Antibodies
Cayman Chemical Oleic Acid (sodium salt), Purity: ≥80%, CAS: 143-19-1, 100 g
A monounsaturated fatty acid; a major component of membrane phospholipids; inhibits collagen-stimulated platelet aggregation at 10 µg/ml; inhibits fMLF-induced neutrophil aggregation and degranulation at 5 µM; induces release of intracellular calcium in human platelets at 60 µM; increases TNF-α, IL-8, IL-6, and IL-1β production, neutrophil accumulation, and apoptotic and necrotic cell death in mouse lung
Cayman Chemical Acetyl-β-methylcholine (chloride), Purity: ≥95%, CAS: 62-51-1, 25 g
A muscarinic agonist; decreases heart rate and blood pressure and increases the airway pressure time index in a dose-dependent manner in wild-type mice
Cayman Chemical 4'-hydroxy Chalcone, Purity: ≥98%, CAS: 2657-25-2, 50 g
A chalcone metabolite; estrogenic and cytotoxic in MCF-7 cells at concentrations higher than 100 nM; inhibits TNF-α-induced NF-κB signaling and the trypsin-, chymotrypsin-, and caspase-like proteolytic activities of the 26S proteasome in K562 cells in a dose-dependent manner; reduces growth of K562, U937, and Jurkat cancer cell lines in a dose-dependent manner without effecting viability of PBMCs; inhibits GSH-RD (IC50 = 47.3 μM) in vitro in a reversible and non-competitive manner
Cayman Chemical Acetosyringone, Purity: ≥98%, CAS: 2478-38-8, 1 g
A phenol secreted by wounded plant tissues; induces expression of virulence A genes and chemotaxis in A. tumefaciens strains that contain a tumor-inducing plasmid used to transfer genetic information to plant cells; widely used to increase efficacy of genetic transformation for the creation of genetically modified dicotyledonous and monocotyledonous plants
ABclonal Technology 488 anti-Human CD300 a/c
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways This gene is located on chromosome 17 in a cluster with all but one of the other family members Multiple transcript variants encoding different isoforms have been found for this gene
Cayman Chemical 5,6-Dihydrouridine, Purity: ≥95%, CAS: 5627-05-4, 1 g
A pyrimidine nucleoside and derivative of uridine; present in tRNA from bacteria, eukaryotes, and some archaea; inhibits E. coli cytidine deaminase in a cell-free assay (Ki = 3.4 µM); serum levels are increased in patients with prostate cancer and positively correlated with lethality
Cayman Chemical p-Nitrophenyl β-D-Galactopyranoside, Purity: ≥98%, CAS: 3150-24-1, 5 g
A β-D-galactosidase chromogenic substrate; cleavage by β-D-galactosidase releases p-nitrophenol, which can be quantified by colorimetric detection at 420 nm as a measure of β-D-galactosidase activity
Cayman Chemical Loxoprofen (sodium salt), Purity: ≥98%, CAS: 80382-23-6, 5 g
An NSAID and a prodrug form of loxoprofen-SRS; inhibits COX-1 and COX-2 in isolated human whole blood (IC50s = 6.5 and 13.5 µM, respectively); reduces acetic acid-induced writhing in mice and carrageenan-induced paw edema and LPS-induced fever in rats (ED30s = 20.1, 0.7, and 2.79 mg/kg, respectively)
Cayman Chemical Goat ntIGST IgG SureLIght 1ea
Goat anti-GST (Glutathione-S-Transferase) IgG conjugated to SureLight PerCP Antibody: Goat polyclonal anti-GST IgG Dye: SureLight™ Peridinin-Chlorophyll (PerCP) Excitation max. λ: 483 nm Emission max. λ: 673 nm Uses: Flow cytometry/Fluorescence-activated cell sorting, Protein microarrays
Cayman Chemical N-Nitrosomethylisopropylamine, Purity: ≥90%, CAS: 30533-08-5, 500 mg
An N-nitrosamine; induces tumor formation in mice
Cayman Chemical STY-BODIPY, Purity: ≥95%, CAS: 2383063-37-2, 5 mg
A fluorogenic probe for radical-trapping antioxidant activity; co-autoxidation with a hydrocarbon co-substrate can be quantified by monitoring the loss of absorbance at 571 nm; has been used to measure the activity of radical-trapping antioxidants, as well as the kinetics and stoichiometry of RTA reactions in cell-free assays
Cayman Chemical 1,10-Phenanthroline (hydrate), Purity: ≥98%, CAS: 5144-89-8, 100 g
A metal chelator and inhibitor of metalloproteases; inhibits zinc-dependent hydrolysis of Fa-Gly-Leu-NH2 by B. subtilis neutral protease and B. thermoproteolyticus thermolysin; fungistatic against P. verrucosa (MIC = 0.8 μg/ml); inhibits zinc-induced P. verrucosa metallo-type peptidase activity; induces uncoupling of and inhibits egg production by adult S. mansoni worm pairs from 0.5-150 μM; reduces worm burden in a mouse model of S. mansoni infection at 20 mg/kg per day
Cayman Chemical 5fluoro PB22 N 3fluoropen
Differs from 5-fluoro PB-22 by having the fluorine atom at the 3 position, rather than the terminal 5 position, of the alkyl group; intended for forensic and research purposes
Cayman Chemical JWH 203 N 5hydroxypentyl m
An internal standard for the quantification of JWH 203 N-(5-hydroxypentyl) metabolite by GC- or LC-MS